Naproxen & Sumatriptan Tablets Sumatriptan + Naproxen Uses Sumatriptan+Naproxen is used in the treatment of migraine. How Sumatriptan + Naproxen works Sumatriptan + Naproxen is a combination of two medicines: Sumatriptan and Naproxen that treat migraine. Sumatriptan is a selective 5HT1-receptor agonist which relieves headache by narrowing the widened blood vessels in the head. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) which blocks the release of certain chemical messengers and decreases general inflammation and pain caused due to migraine
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