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'understood safety profiles'

Items tagged with 'understood safety profiles'

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COVID-19 MEDICINES

ivermectin for humans 12mg Tablet ₹ 50 / Stripe Get Latest Price Strength 12mg Packaging Type Strip Prescription Required Yes Composition (Salts) Ivermectin Usages Covid 19 Although vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), have been developed and distributed, major challenges remain regarding vaccine production and allocation.1 The identification of inexpensive, widely available, and effective therapies against Covid-19 is of great importance. The repurposing of existing medicines that are widely available and that have reasonably well understood safety profiles has appeal.2 One drug that has received considerable public use and interest is ivermectin, which is typically used as an antiparasitic drug. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection (e.g., scabies).3 The in vitro antiviral activity of ivermectin has been explored against a spectrum of viruses, including severe acute respiratory syndrome coronavirus 1, human immunodeficiency virus, dengue virus, Zika virus, yellow fever virus, West Nile virus, Hendra virus, chikungunya virus, Semliki Forest virus, Sindbis virus, and avian influenza virus.4 More than 60 randomized trials of ivermectin for the treatment of Covid-19 have been registered, and findings have been reported for as many as 31 clinical trials.5 The results have been discordant, and various review groups interpret the evidence differently — some advocating for benefits of ivermectin, and others reticent to conclude a benefit.6-8 However, most trials have been small, and several have been withdrawn from publication owing to concerns about credibility.9 To evaluate the efficacy of ivermectin for the prevention of progression of Covid-19 resulting in hospitalization among outpatients with SARS-CoV-2 infection, we conducted a randomized, placebo-controlled, adaptive platform trial (TOGETHER) in the state of Minas Gerais, Brazil. Although various interventions were assessed in this trial, we report here on the use of ivermectin at a dose of 400 μg per kilogram of body weight for 3 days as compared with placebo.

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COVID-19 MEDICINES

iveremectin Ivecop 6 Mg Tablet ₹ 35 / Stripe Get Latest Price Strength 6mg Packaging Type Strip Prescription Required Yes Composition (Salts) Ivermectin Usages Covid 19 Although vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), have been developed and distributed, major challenges remain regarding vaccine production and allocation.1 The identification of inexpensive, widely available, and effective therapies against Covid-19 is of great importance. The repurposing of existing medicines that are widely available and that have reasonably well understood safety profiles has appeal.2 One drug that has received considerable public use and interest is ivermectin, which is typically used as an antiparasitic drug. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection (e.g., scabies).3 The in vitro antiviral activity of ivermectin has been explored against a spectrum of viruses, including severe acute respiratory syndrome coronavirus 1, human immunodeficiency virus, dengue virus, Zika virus, yellow fever virus, West Nile virus, Hendra virus, chikungunya virus, Semliki Forest virus, Sindbis virus, and avian influenza virus.4 More than 60 randomized trials of ivermectin for the treatment of Covid-19 have been registered, and findings have been reported for as many as 31 clinical trials.5 The results have been discordant, and various review groups interpret the evidence differently — some advocating for benefits of ivermectin, and others reticent to conclude a benefit.6-8 However, most trials have been small, and several have been withdrawn from publication owing to concerns about credibility.9 To evaluate the efficacy of ivermectin for the prevention of progression of Covid-19 resulting in hospitalization among outpatients with SARS-CoV-2 infection, we conducted a randomized, placebo-controlled, adaptive platform trial (TOGETHER) in the state of Minas Gerais, Brazil. Although various interventions were assessed in this trial, we report here on the use of ivermectin at a dose of 400 μg per kilogram of body weight for 3 days as compared with placebo.

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Anti Anxiety Medicines

Tiatan Tianeptine 50mg Sodium Tablets Stablon ₹ 399 / Stripe Get Latest Price Product Brochure Strength 37.5 mg Packaging Size 10x10 Brand Tiatan 50 Shelf life 2 Year Country of Origin Made in India Tiatan 50mg Tianeptine Sodium TabletsBrand Names: Tiatan, Stablon (in some regions)Composition: Tianeptine SodiumStrength: 50 mg per tabletManufacturer: ApexPackaging: Typically available in blister packs containing 10 tabletsTreatment: Major Depressive Disorder (MDD)Product Description:Tiatan 50mg Tianeptine Sodium Tablets contain Tianeptine Sodium, an atypical antidepressant primarily used for the treatment of major depressive disorder (MDD). Tianeptine has a unique mechanism of action compared to traditional antidepressants; it modulates glutamatergic neurotransmission and enhances neuroplasticity, which may contribute to its antidepressant effects.Indications:Major Depressive Disorder (MDD): Alleviates symptoms such as persistent sadness, loss of interest in activities, and feelings of hopelessness.Dosage and Administration:For Adults: The usual recommended dose is 12.5 mg taken three times daily before meals. Since Tiatan is available in a 50 mg strength, it is crucial to adjust the dosage accordingly under medical supervision to avoid overdosing.Administration: Tablets should be swallowed whole with water, preferably before meals. Do not crush or chew the tablets.Common Side Effects:NauseaDizzinessDry mouthConstipationDrowsinessAbdominal painPrecautions:Medical Supervision: Use only under the guidance of a qualified healthcare professional.Avoid Abrupt Discontinuation: Stopping the medication suddenly may lead to withdrawal symptoms.Potential for Misuse: Tianeptine has a potential for dependence; adhere strictly to the prescribed dosage.Interactions: Inform your doctor about any other medications or supplements you are taking.Packaging:Tiatan 50mg Tianeptine Sodium Tablets are usually packaged in blister packs containing 10 tablets, protecting the medication from moisture and contamination.Note: Due to the high strength of 50 mg per tablet, extreme caution is advised. Always consult a healthcare provider for appropriate dosing to minimize the risk of side effects or overdose. Regular monitoring may be necessary to assess efficacy and safety during treatment.

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Antibiotics

Dalcinex Clindamycin 300mg/2ml Injection Cleocin ₹ 320 / Vial Get Latest Price Product Brochure Strength 300 mg Packaging Type Vial Form Injection Shelf life 24 months Prescription/Non prescription Non prescription Country of Origin Made in India Dalcinex 300 mg Injection Brand Names: Dalcinex, Cleocin (original brand name: Cleocin) Composition: Clindamycin Strength: 300 mg per 2 ml vial Manufacturer: Various manufacturers, including Pfizer and Sun Pharmaceutical Industries Ltd. Packaging: Typically available in a 2 ml vial containing 300 mg of Clindamycin Treatment: Dalcinex 300 mg Injection is used for treating a variety of serious bacterial infections, particularly those caused by anaerobic bacteria and some Gram-positive bacteria. Product Description: Dalcinex 300 mg Injection contains Clindamycin, an antibiotic that belongs to the lincosamide class. It works by inhibiting bacterial protein synthesis, thereby stopping the growth and spread of bacteria. Clindamycin is particularly effective against anaerobic bacteria and is often used in situations where other antibiotics, such as penicillin, are not effective or suitable. Common indications for Dalcinex 300 mg Injection include: Bone and Joint Infections: Such as osteomyelitis. Severe Skin and Soft Tissue Infections: Including abscesses, cellulitis, and infected wounds. Respiratory Tract Infections: Such as pneumonia, particularly when caused by susceptible bacteria. Gynecological Infections: Including pelvic inflammatory disease (PID). Intra-abdominal Infections: Such as peritonitis. Septicemia: For the treatment of bloodstream infections caused by susceptible bacteria. Dosage and Administration: For Adults: The typical dose is 300 mg to 600 mg every 6 to 8 hours, depending on the severity of the infection and patient response. For Children: The dose is usually based on body weight and the specific infection being treated. Administration: Dalcinex is administered by intramuscular (IM) or intravenous (IV) injection. The method of administration and the dosage schedule will be determined by a healthcare provider based on the type and severity of the infection. It is important to follow the healthcare provider’s instructions regarding the dosage and duration of treatment to ensure the infection is fully treated and to reduce the risk of antibiotic resistance. Common side effects of Dalcinex 300 mg Injection may include: Injection site reactions (pain, redness, swelling) Nausea Diarrhea Rash Serious side effects can include severe allergic reactions (anaphylaxis), Clostridium difficile-associated diarrhea, and liver dysfunction. If any severe side effects occur, discontinue use and seek immediate medical attention. Packaging: Dalcinex 300 mg Injection is typically available in a 2 ml vial, packaged individually or in boxes containing multiple vials. Dalcinex 300 mg Injection (Clindamycin) is a potent antibiotic used for treating a wide range of serious bacterial infections. Proper administration by a healthcare provider, adherence to prescribed dosages, and monitoring for side effects are essential to ensure the effectiveness of the treatment and the safety of the patient

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STEROID INJECTIONS

Testosterone Undecanoate Injection 1000 mg Strength 1000mg/4ml Brand Cernos Drug Strength 1000mg Brand Name Cernos Depot Manufacturer Akums Drugs & Pharmaceuticals Ltd Packaging Size 4ml Ampoule Form Ampoule HSN Code 30043913 Country of Origin Made in India Cernos Depot Injection is a medicine used in the treatment of male hypogonadism caused due to low testosterone levels. It is only prescribed to men with known medical conditions. It helps in restoring the level of testosterone in the male body. Cernos Depot Injection is a testosterone replacement therapy medication used to treat male hypogonadism, a condition in which the body does not produce enough testosterone. It is a long-acting injection that is given every 10-12 weeks. Cernos Depot Injection is a safe and effective treatment for male hypogonadism, and it can help to improve symptoms such as low sex drive, fatigue, and muscle weakness. Here are some of the key features of Cernos Depot Injection: Long-acting: Cernos Depot Injection is a long-acting injection that is given every 10-12 weeks. This makes it a convenient and easy-to-use treatment option. Effective: Cernos Depot Injection is a safe and effective treatment for male hypogonadism. It has been shown to improve symptoms such as low sex drive, fatigue, and muscle weakness. Approved by the FDA: Cernos Depot Injection is approved by the FDA for the treatment of male hypogonadism. This means that it has been evaluated for safety and efficacy by a rigorous scientific process. If you are a man who is experiencing symptoms of male hypogonadism, talk to your doctor about Cernos Depot Injection. It may be the right treatment option for you. Here are some additional details about Cernos Depot Injection: It is a synthetic form of testosterone. It is injected into the muscle. It starts working within a few days of injection. It can help to improve symptoms such as low sex drive, fatigue, and muscle weakness. It is important to follow your doctor's instructions when using Cernos Depot Injection.

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STEROID INJECTIONS

Drostanolone propionate Injection 100 mg Drostanolone Propionate Injection is an anabolic steroid primarily used by athletes and bodybuilders to enhance muscle definition and strength. It belongs to a class of drugs known as androgens, which stimulate the development of male characteristics. This injection is commonly utilized to improve athletic performance and achieve a lean, sculpted physique. It is administered under medical supervision to ensure safety and effectiveness in achieving desired fitness goals

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Anti hiv medicine

Hepcinat plus tablet contains active agents Daclatasvir and Sofosbuvir. It is an antiviral medication used to treat chronic hepatitis C virus (HCV) infections. Hepatitis C infection is a liver disease caused by the hepatitis C virus (HCV). Talk to your doctor if you have liver problems other than hepatitis C infection, had a liver transplant, diabetes, heart disorders, severe kidney problems, or are on dialysis before taking Hepcinat plus tablet. Your physician will perform blood tests to check for hepatitis B virus infection before starting treatment with this medicine, as this medicine can reactivate the hepatitis B virus. Hepatitis B virus reactivation can cause serious liver problems and liver failure. It is vital to inform your doctor if you are taking or have taken any medication for heart problems in the past months. Elderly patients may be more susceptible to the side effects of Hepcinat plus tablet and may require lower doses or closer monitoring during treatment. The safety and effectiveness of pediatric patients have not been established. These medications should only be used in children under the guidance of a pediatric specialist.

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